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Anti-HSP60 antibody

产品货号 产品 品牌 单位 存货 价格 促销价 数量  
AB-06-2279
Anti-HSP60 antibody
洱畔/Erpan Tech 有货

产品特性        

Product Cat#: AB-06-2279
Product type: Primary antibody
Antigen: HSP60
Immunogen: Peptide
Species immunized: Rabbit
Isotype: IgG
Applications: Western Blot (1:6000-1:10000); Immunohistochemistry; Immunocytochemistry
Reactivity: Mouse, Rat and Human
Clonality (clone number): Polyclonal
Form: Liquid
Buffer: Tris-HCl buffer (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.
Concentration: 1 mg/ml
Purity: Immunogen affinity purified
Storage: Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles.
Alternative names: 60 kDa chaperonin antibody
60 kDa heat shock protein, mitochondrial antibody
CH60_HUMAN antibody
Chaperonin 60 antibody
Chaperonin, 60-KD antibody
CPN60 antibody
Fa04a05 antibody
GROEL antibody
Heat shock 60kDa protein 1 (chaperonin) antibody
Heat shock protein 60 antibody
Heat shock protein 65 antibody
Heat shock protein family D (Hsp60) member 1 antibody
HLD4 antibody
Hsp 60 antibody
HSP 65 antibody
HSP-60 antibody
HSP60 antibody
HSP65 antibody
HSPD1 antibody
HuCHA60 antibody
Mitochondrial matrix protein P1 antibody
P60 lymphocyte protein antibody
Short heat shock protein 60 Hsp60s1 antibody
SPG16 antibody
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靶标信息

Chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp10, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix (PubMed:1346131, PubMed:11422376). The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10. This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components. Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein (Probable).

产品来源

洱畔科技实验室

文件下载

MSDS-AB-06-2279.pdf (下载204 )