Anti-HECW2 antibody
产品特性
| Product Cat#: | AB-07-0629 |
| Product type: | Primary antibody |
| Antigen: | HECW2 |
| Immunogen: | A synthetic peptide derived from human HECW2. The exact amino-acid sequence is proprietary. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2500); ELISA (1:5000) |
| Reactivity: | Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | PBS (without Mg2+ and Ca2+ ), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | E3 ubiquitin-protein ligase HECW2; EC 6.3.2.-; HECT, C2 and WW domain-containing protein 2; NEDD4-like E3 ubiquitin-protein ligase 2 |
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靶标信息
E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73 (PubMed:12890487). Involved in the regulation of mitotic metaphase/anaphase transition (PubMed:24163370).
产品来源
洱畔科技实验室
