Anti-HDAC9 antibody
产品特性
| Product Cat#: | AB-06-2116 |
| Product type: | Primary antibody |
| Antigen: | HDAC9 |
| Immunogen: | Purified recombinant fragment of human HDAC9 expressed in E. Coli. |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:200-1:2000); Flow Cytometry (1:100-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (C4-B7) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | ProA affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | HD 7 antibody |
| HD 7B antibody | |
| HD 9 antibody | |
| HD7 antibody | |
| HD7B antibody | |
| HD9 antibody | |
| HDAC 7 antibody | |
| HDAC 7B antibody | |
| HDAC 9 antibody | |
| HDAC 9B antibody | |
| HDAC 9FL antibody | |
| HDAC antibody | |
| HDAC7B antibody | |
| HDAC9 antibody | |
| HDAC9_HUMAN antibody | |
| HDAC9B antibody | |
| HDAC9FL antibody | |
| HDRP antibody | |
| Histone deacetylase 4/5 related protein antibody | |
| Histone deacetylase 7 antibody | |
| Histone deacetylase 7B antibody | |
| Histone deacetylase 9 antibody | |
| Histone deacetylase 9A antibody | |
| Histone deacetylase related protein antibody | |
| Histone deacetylase-related protein antibody | |
| KIAA0744 antibody | |
| MEF2 interacting transcription repressor MITR antibody | |
| MEF2 interacting transcription repressor protein antibody | |
| MEF2-interacting transcription repressor MITR antibody | |
| MITR antibody |
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靶标信息
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription.
Isoform 3 lacks active site residues and therefore is catalytically inactive. Represses MEF2-dependent transcription by recruiting HDAC1 and/or HDAC3. Seems to inhibit skeletal myogenesis and to be involved in heart development. Protects neurons from apoptosis, both by inhibiting JUN phosphorylation by MAPK10 and by repressing JUN transcription via HDAC1 recruitment to JUN promoter.
产品来源
洱畔科技实验室
