Anti-HDAC4 antibody
产品特性
| Product Cat#: | AB-06-2110 |
| Product type: | Primary antibody |
| Antigen: | HDAC4 |
| Immunogen: | Purified recombinant fragment of human HDAC4 (AA: 456-592) expressed in E. Coli. |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:200-1:2000); Flow Cytometry (1:100-1:200); Immunocytochemistry (1:100-1:500) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (2E-6E) |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | ProA affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | AHO3 antibody |
| BDMR antibody | |
| EC 3.5.1.98 antibody | |
| HA6116 antibody | |
| HD 4 antibody | |
| HD4 antibody | |
| HDAC 4 antibody | |
| HDAC A antibody | |
| HDAC4 antibody | |
| HDAC4_HUMAN antibody | |
| HDACA antibody | |
| Histone deacetylase 4 antibody | |
| Histone Deacetylase A antibody | |
| KIAA0288 antibody |
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靶标信息
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. Deacetylates HSPA1A and HSPA1B at ‘Lys-77’ leading to their preferential binding to co-chaperone STUB1 (PubMed:27708256).
产品来源
洱畔科技实验室