Anti-FOXP3 antibody
产品特性
| Product type: | Primary antibody |
| Antigen: | FOXP3 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Flow Cytometry (1:40-1:100); Immunocytochemistry (1:20-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (JF0898) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | AIID antibody |
| DIETER antibody | |
| Forkhead box P3 antibody | |
| Forkhead box protein P3 antibody | |
| FOXP3 antibody | |
| FOXP3_HUMAN antibody | |
| FOXP3delta7 antibody | |
| Immune dysregulation polyendocrinopathy enteropathy X linked antibody | |
| Immunodeficiency polyendocrinopathy enteropathy X linked antibody | |
| IPEX antibody | |
| JM2 antibody | |
| MGC141961 antibody | |
| MGC141963 antibody | |
| OTTHUMP00000025832 antibody | |
| OTTHUMP00000025833 antibody | |
| OTTHUMP00000226737 antibody | |
| PIDX antibody | |
| Scurfin antibody | |
| XPID antibody |
展开
靶标信息
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity (By similarity).
产品来源
洱畔科技实验室
