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Anti-FOXN4 antibody

产品货号 产品 品牌 单位 存货 价格 促销价 数量  
AB-07-0522
Anti-FOXN4 antibody
洱畔/Erpan Tech 有货

产品特性        

Product Cat#: AB-07-0522
Product type: Primary antibody
Antigen: FOXN4
Immunogen: A synthetic peptide derived from human FOXN4 . The exact amino-acid sequence is proprietary.
Species immunized: Rabbit
Isotype: IgG
Applications: Western Blot: 1:500~1:3000 ELISA: 1:10000
Reactivity: Human
Clonality (clone number): Polyclonal
Form: Liquid
Buffer: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/ml
Purity: Antigen affinity chromatography
Storage: Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles.
Alternative names: FOXN4 ;Forkhead box protein N4; FOXN4
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靶标信息

Transcription factor essential for neural and some non-neural tissues development, such as retina and lung respectively. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5′-ACGC-3′. During development of the central nervous system, is required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates through activating DLL4-NOTCH signaling. Also acts synergistically with ASCL1/MASH1 to activate DLL4-NOTCH signaling and drive commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the atrioventricular canal and is indirectly required for patterning the distal airway during lung development (By similarity).

产品来源

洱畔科技实验室

文件下载

MSDS-AB-07-0522.pdf (下载140 )