Anti-FKBP38 antibody
产品特性
| Product Cat#: | AB-06-1731 |
| Product type: | Primary antibody |
| Antigen: | FKBP38 |
| Immunogen: | KLH conjugated synthetic peptide derived from human FKBP38 255-350/412 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000) |
| Reactivity: | Human, Mouse, Rat, Chicken, Dog, Cow, Horse |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01 M TBS(pH7.4) with 1% BSA; 0.03% Proclin 300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 38 kDa FK 506 binding protein homolog |
| 38 kDa FK506-binding protein | |
| 38 kDa FKBP | |
| 38kDa antibody FK506 binding protein 8 | |
| FK506 binding protein 8, 38kDa | |
| FK506 binding protein, 38kDa | |
| FK506-binding protein 8 | |
| FKBP 38 | |
| FKBP-38 | |
| FKBP-8 | |
| FKBP8 | |
| FKBP8_HUMAN | |
| FKBPR38 | |
| HFKBP38 | |
| Peptidyl-prolyl cis-trans isomerase FKBP8 | |
| PPIase FKBP8 | |
| Rotamase |
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靶标信息
Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.
产品来源
洱畔科技实验室