Anti-FCGR1A/CD64 antibody
产品特性
| Product type: | Primary antibody |
| Antigen: | FCGR1A/CD64 |
| Immunogen: | KLH conjugated synthetic peptide derived from human CD64/IGFR1 101-200/374 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Flow Cytometry (1μg /test) |
| Reactivity: | Human, Mouse, Rat, Pig, Cow |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CD 64 |
| CD64 antigen | |
| CD64A | |
| Fc fragment of IgG high affinity Ia receptor | |
| F Fc fragment of IgG, high affinity Ia, receptor (CD64) | |
| Fc fragment of IgG, high affinity Ia, receptor for | |
| Fc fragment of IgG, high affinity Ib, receptor (CD64) | |
| Fc fragment of IgG, high affinity Ib, receptor for | |
| Fc fragment of IgG, high affinity Ic, receptor (CD64) | |
| Fc fragment of IgG, high affinity Ic, receptor for | |
| Fc gamma receptor | |
| Fc gamma receptor I A1 | |
| Fc gamma receptor I | |
| Fc gamma receptor I B2 | |
| Fc gamma RI | |
| Fc of IgG high affinity Ia receptor | |
| Fc-gamma RIC | |
| FCG 1 | |
| FCG1 | |
| FcgammaRI | |
| FCGR 1 | |
| FCGR1 | |
| FCGR1A | |
| FCGR1B | |
| FCGR1C | |
| FcRI | |
| FCRIC | |
| IGFR 1 | |
| IGFR1 | |
| IGFRB | |
| IGFRC | |
| IgG Fc receptor I | |
| IgG Fc receptor IC | |
| Immunoglobulin G Fc receptor I | |
| Immunoglobulin G Fc receptor IB |
展开
靶标信息
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity (By similarity).
产品来源
洱畔科技实验室
