Anti-FADD antibody
产品特性
| Product Cat#: | AB-07-0496 |
| Product type: | Primary antibody |
| Antigen: | FADD |
| Immunogen: | A synthetic peptide derived from human FADD . The exact amino-acid sequence is proprietary. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Immunohistochemistry: 1:50~1:100 |
| Immunofluorescence: 1:100~1:500 ELISA: 1:20000 | |
| Reactivity: | Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | FADD/FAS-associating death domain-containing protein, MORT1, Mediator of receptor induced toxicity |
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靶标信息
Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.
产品来源
洱畔科技实验室
