Anti-E2F3 antibody
产品特性
| Product Cat#: | AB-06-1481 |
| Product type: | Primary antibody |
| Antigen: | E2F3 |
| Immunogen: | KLH conjugated synthetic peptide derived from human E2F3 381-465/465 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot ( 1:800-1:2000 ) |
| Reactivity: | Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit and Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer ( pH7.4 ), 1 % BSA, 40 % glycerol, 0.05 % NaN3, 0.03 % Proclin300. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | DKFZp686C18211 |
| E2F 3 | |
| E2F Transcription Factor 3 | |
| KIAA0075 | |
| MGC104598 | |
| Transcription Factor E2F 3 | |
| E2F3_HUMAN | |
| Transcription Factor E2F3 | |
| E2F-3. |
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靶标信息
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5′-TTTC[CG]CGC-3′ found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3 binds specifically to RB1 in a cell-cycle dependent manner. Inhibits adipogenesis, probably through the repression of CEBPA binding to its target gene promoters (By similarity).
产品来源
洱畔科技实验室
