Anti-DVL1 antibody
Specifications
| Product Cat#: | AB-06-1464 |
| Product type: | Primary antibody |
| Antigen: | DVL1 |
| Immunogen: | KLH conjugated synthetic peptide derived from human DVL1 21-100/695 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Flow Cytometry (4 ug/Test); Immunohistochemistry-Paraffin (1:500-1:800) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10 mM TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Dishevelled 1 |
| Dishevelled | |
| Dishevelled dsh homolog 1 | |
| Dishevelled1 | |
| DSH homolog 1 | |
| Dvl | |
| MGC54245 | |
| Segment polarity protein dishevelled homolog DVL 1 | |
| Segment polarity protein dishevelled homolog DVL1 |
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靶标信息
Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ).
产品来源
洱畔科技实验室
