Anti-DNCLI1 antibody
产品特性
| Product type: | Primary antibody |
| Antigen: | DNCLI1 |
| Immunogen: | KLH conjugated synthetic peptide derived from human DNCLI1 451-550/523 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry-Paraffin (1:500-1:800) |
| Reactivity: | Human, Mouse, Rat, Chicken |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Cytoplasmic dynein 1 light intermediate chain 1 |
| cytosolic | |
| DC1L1_HUMAN | |
| DLC-A | |
| DNCLI1 | |
| Dync1li1 | |
| Dynein cytoplasmic 1 light intermediate chain 1 | |
| Dynein cytoplasmic light intermediate polypeptide 1 | |
| Dynein light chain A | |
| Dynein light intermediate chain 1 | |
| Dynein light intermediate chain 1 cytosolic | |
| FLJ10219 |
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靶标信息
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress through the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.
产品来源
洱畔科技实验室
