Anti-DARS2 antibody
产品特性
| Product Cat#: | AB-06-1320 |
| Product type: | Primary antibody |
| Antigen: | DARS2 |
| Immunogen: | KLH conjugated synthetic peptide derived from human DARS2 551-645/645 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot |
| Reactivity: | Human, Mouse, Rat, Cow |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01 M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Aspartate tRNA ligase 2 mitochondrial |
| Aspartate tRNA ligase | |
| Aspartate tRNA ligase mitochondrial | |
| Aspartyl tRNA synthetase 2 (mitochondrial) | |
| Aspartyl tRNA synthetase mitochondrial | |
| AspRS | |
| FLJ10514 | |
| SYDM_HUMAN | |
| LBSL | |
| MT ASPRS |
靶标信息
Serine/threonine kinase which is involved in the regulation of apoptosis, autophagy, transcription, translation and actin cytoskeleton reorganization. Involved in the regulation of smooth muscle contraction. Regulates both type I (caspase-dependent) apoptotic and type II (caspase-independent) autophagic cell deaths signal, depending on the cellular setting. Involved in regulation of starvation-induced autophagy. Regulates myosin phosphorylation in both smooth muscle and non-muscle cells. In smooth muscle, regulates myosin either directly by phosphorylating MYL12B and MYL9 or through inhibition of smooth muscle myosin phosphatase (SMPP1M) via phosphorylation of PPP1R12A; the inhibition of SMPP1M functions to enhance muscle responsiveness to Ca2+ and promote a contractile state.
产品来源
洱畔科技实验室
