Anti-D4S234E antibody
产品特性
| Product Cat#: | AB-06-1312 |
| Product type: | Primary antibody |
| Antigen: | D4S234E |
| Immunogen: | KLH conjugated synthetic peptide derived from human NEEP21 1-100/185 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry-Paraffin (1:500-1:1000) |
| Reactivity: | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01 M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | NSG1_HUMAN |
| Brain neuron cytoplasmic protein 1 | |
| Brain specific mRNA b | |
| Bsmrb | |
| Neuron-specific gene family member 1 | |
| Neuron-specific protein family member 1 | |
| NSG1 | |
| D4S234 | |
| NEEP21 |
展开
靶标信息
Plays a role in the recycling mechanism in neurons of multiple receptors, including AMPAR, APP and L1CAM and acts at the level of early endosomes to promote sorting of receptors toward a recycling pathway. Regulates sorting and recycling of GRIA2 through interaction with GRIP1 and then contributes to the regulation of synaptic transmission and plasticity by affecting the recycling and targeting of AMPA receptors to the synapse (By similarity). Is required for faithful sorting of L1CAM to axons by facilitating trafficking from somatodendritic early endosome or the recycling endosome (By similarity). In an other hand, induces apoptosis via the activation of CASP3 in response to DNA damage
产品来源
洱畔科技实验室
