产品特性

Product Cat#:	AB-06-4946
Product type:	Primary antibody
Antigen:	CENPU
Immunogen:	Synthesized peptide derived from human protein CENPU. AA range: 160-240.
Species immunized:	Rabbit
Isotype:	IgG
Applications:	Western Blot (1:400-1:2000)
Reactivity:	Human
Clonality (clone number):	Polyclonal
Form:	Liquid
Buffer:	1*PBS buffer (pH7.4), 50% Glycerol, 0.02% NaN3.
Concentration:	1 mg/ml
Purity:	Immunogen affinity purified.
Storage:	Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles.
Conjugate:	Unconjugated
Alternative names:	Centromere Protein U; KLIP1; PBIP1; Polo-Box-Interacting Protein 1; CENP-50; CENP-U; MLF1IP; Interphase Centromere Complex Protein 24; Centromere Protein Of 50 KDa; MLF1 Interacting Protein; KSHV Latent Nuclear Antigen Interacting Protein 1; KSHV Latent Nuclear Antigen-Interacting Protein 1; MLF1-Interacting Protein; CENPU50; CENP50; ICEN24

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靶标信息

Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Plays an important role in the correct PLK1 localization to the mitotic kinetochores. A scaffold protein responsible for the initial recruitment and maintenance of the kinetochore PLK1 population until its degradation. Involved in transcriptional repression.

产品来源

洱畔科技实验室