Anti-Cellubrevin antibody
产品特性
| Product Cat#: | AB-06-1025 | |||||||||
| Product type: | Primary antibody | |||||||||
| Antigen: | Cellubrevin | |||||||||
| Immunogen: | Synthetic peptide conjugated to KLH within N-terminal human Cellubrevin. | |||||||||
| Species immunized: | Rabbit | |||||||||
| Isotype: | IgG | |||||||||
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry (1:40-1:200); Flow Cytometry (1:40-1:100); Immunocytochemistry (1:40-1:200); Immunofluorescence | |||||||||
| Reactivity: | Human, Mouse, Rat | |||||||||
| Clonality (clone number): | Monoclonal (JG36-31) | |||||||||
| Form: | Liquid | |||||||||
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% Glycerol, 0.05% NaN3. | |||||||||
| Concentration: | 1 mg/ml | |||||||||
| Purity: | Protein A affinity purified | |||||||||
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. | |||||||||
| Alternative names: | CEB antibody | Cellubrevin antibody | Synaptobrevin 3 antibody | Synaptobrevin-3 antibody | VAMP 3 antibody | VAMP-3 antibody | VAMP3 antibody | VAMP3_HUMAN antibody | Vesicle associated membrane protein 3 antibody | Vesicle-associated membrane protein 3 antibody |
靶标信息
Vesicle-associated membrane proteins, known as VAMPs, also designated synaptobrevins, include VAMP-1, VAMP-2, VAMP-3 (cellubrevin), and synaptotagmin, a protein that may function as an inhibitor of exocytosis. VAMP proteins are vesicular factors that are important components of the machinery controlling docking and/or fusion of secretory vesicles with their target membrane. Synaptosomal-associated proteins, known as SNAPs, including alpha- and gamma-SNAP, are cytoplasmic proteins that bind to a membrane receptor complex composed of VAMP, SNAP 25 and syntaxin. Pancreatic beta-cells express VAMP-2 and VAMP-3, and either one or both of these proteins selectively control Ca2+-mediated insulin secretion. In addition, VAMP-2 and VAMP-3 are expressed on GLUT4-containing vesicle membranes isolated from 3T3-Ll adipocytes and are important components of the insulin-dependent translocation of GLUT4 to the cell surface in adipocytes.
产品来源
洱畔科技实验室
