Anti-CDCP1 antibody
产品特性
| Product Cat#: | AB-06-0991 |
| Product type: | Primary antibody |
| Antigen: | CDCP1 |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry (1:180-1:500) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (G3-H11) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 9030022E12Rik antibody |
| AA409659 antibody | |
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| Cdcp1 antibody | |
| CDCP1_HUMAN antibody | |
| CUB domain containing protein 1 antibody | |
| CUB domain-containing protein 1 antibody | |
| E030027H19Rik antibody | |
| FLJ13772 antibody | |
| FLJ22375 antibody | |
| FLJ22969 antibody | |
| Membrane glycoprotein gp140 antibody | |
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| OTTHUMP00000164120 antibody | |
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| RGD1305578 antibody | |
| SIMA 135 antibody | |
| SIMA135 antibody | |
| Subtractive immunization M plus HEp3 associated 135 kDa protein antibody | |
| Subtractive immunization M plus HEp3-associated 135 kDa protein antibody | |
| Transmembrane and associated with src kinases antibody | |
| TRASK antibody |
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靶标信息
CDCP1 (CUB-domain-containing protein 1) contains three extracellular CUB domains, a transmembrane domain, and two putative cytoplasmic tyrosine phosphorylation sites. Phosphorylation of the gp140 and p80 proteins is mediated by Src family kinases at various tyrosine residues, including Tyr 734. PTP family members mediate the desphosphorylation of CDCP1. The conversion of gp140 to p80 prolongs the phosphorylation state, which may affect signaling in epithelial wounds. CDCP1 acts as a marker for hematopoetic cells and also exhibits high expression in metastatic colon and breast tumors.
产品来源
洱畔科技实验室