Anti-CD14 antibody
产品特性
| Product Cat#: | AB-06-0851 | ||||||||||||
| Product type: | Primary antibody | ||||||||||||
| Antigen: | CD14 | ||||||||||||
| Immunogen: | Recombinant protein | ||||||||||||
| Species immunized: | Rabbit | ||||||||||||
| Isotype: | IgG | ||||||||||||
| Applications: | Western Blot ( 1:800-1:2000 ); Immunohistochemistry ( 1:80-1:200 ); Immunocytochemistry ( 1:80-1:200 ) | ||||||||||||
| Reactivity: | Mouse, Rat and Human | ||||||||||||
| Clonality (clone number): | Monoclonal ( SC69-02 ) | ||||||||||||
| Form: | Liquid | ||||||||||||
| Buffer: | Tris-HCl buffer ( pH7.4 ), 1 % BSA, 40 % glycerol, 0.05 % NaN3. | ||||||||||||
| Concentration: | 1 mg/ml | ||||||||||||
| Purity: | Protein A affinity purified | ||||||||||||
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. | ||||||||||||
| Alternative names: | CD 14 Antibody | CD_antigen=CD14 Antibody | CD14 Antibody | CD14 Antigen Antibody | CD14 Molecule Antibody | CD14_HUMAN Antibody | LPS-R Antibody | Mo2 Antibody | Monocyte Differentiation Antigen CD14 Antibody | Monocyte Differentiation Antigen CD14 Urinary Form Antibody | Monocyte Differentiation Antigen CD14, Membrane-bound Form Antibody | Myeloid Cell Specific Leucine Rich Glycoprotein Antibody | Myeloid Cell-specific Leucine-rich Glycoprotein Antibody |
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靶标信息
Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL–) and mediates the cytokine release induced by LDL–.
产品来源
洱畔科技实验室