Anti-cbx7 antibody
产品特性
| Product Cat#: | AB-06-0795 |
| Product type: | Primary antibody |
| Antigen: | CBX7 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:550-1:2000); Flow Cytometry (1:60-1:100) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (JM44-63) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Cbx 7 antibody |
| CBX7 antibody | |
| Chromobox homolog 7 antibody | |
| Chromobox protein homolog 7 antibody |
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靶标信息
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A ‘Lys-119’, rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at ‘Lys-9’ (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.
产品来源
洱畔科技实验室
