Anti-Caspase-3 antibody (KO Validated)
产品特性
| Product Cat#: | AB-06-0754 |
| Product type: | Primary antibody |
| Antigen: | Caspase-3 |
| Immunogen: | Synthetic peptide within human Caspase-3 aa 60-100. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:1000-1:4000); Immunocytochemistry/Immunofluorescence (1:40-1:100); Immunohistochemistry-Paraffin (1:100-1:200); Flow Cytometry (1:20-1:40); Immunoprecipitation |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal, SR03-01 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 0.05% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | A830040C14Rik antibody |
| Apopain antibody | |
| CASP-3 antibody | |
| CASP3 antibody | |
| CASP3_HUMAN antibody | |
| Casp3a antibody | |
| Caspase 3 antibody | |
| Caspase 3, apoptosis-related cysteine peptidase antibody | |
| Caspase 3, apoptosis-related cysteine protease antibody | |
| Caspase 3, apoptosis-related cysteine protease a antibody | |
| Caspase-3 subunit p12 antibody | |
| CC3 antibody | |
| CPP-32 antibody | |
| CPP32 antibody | |
| CPP32B antibody | |
| Cysteine protease CPP32 antibody | |
| EC 3.4.22.56 antibody | |
| LICE antibody | |
| Mldy antibody | |
| OTTHUMP00000165052 antibody | |
| OTTHUMP00000165053 antibody | |
| OTTHUMP00000165054 antibody | |
| PARP cleavage protease antibody | |
| Procaspase3 antibody | |
| Protein Yama antibody | |
| SCA 1 antibody | |
| SCA-1 antibody | |
| SREBP cleavage activity 1 antibody | |
| Yama antibody |
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靶标信息
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a ‘216-Asp-|-Gly-217’ bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
产品来源
洱畔科技实验室
