Anti-CAMKK2 antibody
产品特性
| Product type: | Primary antibody |
| Antigen: | CAMKK2 |
| Immunogen: | KLH conjugated synthetic peptide derived from human CAMKK2 501-588/588 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry-Paraffin (1:500-800); Flow Cytometry (1ug/test) |
| Reactivity: | Human, Mouse, Rat, Pig, Cow, Horse, Sheep |
| Clonality (clone number): | Monoclonal, JB33-13 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Calcium/calmodulin dependent protein kinase beta |
| Calcium/calmodulin dependent protein kinase kinase 2 | |
| Calcium/calmodulin dependent protein kinase kinase beta | |
| CaM kinase kinase beta | |
| CaM KK beta | |
| CAMKK 2 | |
| CAMKK | |
| CaMKK beta | |
| CAMKK beta protein |
靶标信息
Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5′-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca2+ signals (By similarity). Seems to be involved in hippocampal activation of CREB1 (By similarity). May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching.
产品来源
洱畔科技实验室
