Anti-Calsequestrin 1 antibody
产品特性
| Product type: | Primary antibody |
| Antigen: | Calsequestrin 1 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400); Immunohistochemistry (1:100-1:200); Flow Cytometry (1:40-1:100) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal, JB57-37 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 0.05% NaN3 and 40% Glycerol. |
| Concentration: | 1mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Calmitin antibody |
| Calmitine antibody | |
| Calsequestrin 1 (fast twitch, skeletal muscle) antibody | |
| Calsequestrin antibody | |
| Calsequestrin, cell antibody | |
| Calsequestrin, skeletal muscle isoform antibody | |
| Calsequestrin-1 antibody | |
| CASQ antibody | |
| Casq1 antibody | |
| CASQ1_HUMAN antibody | |
| PDIB1 antibody | |
| Skeletal muscle isoform antibody |
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靶标信息
Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle (PubMed:28895244). Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca2+ ions (PubMed:28895244). Regulates the release of lumenal Ca2+ via the calcium release channel RYR1; this plays an important role in triggering muscle contraction. Negatively regulates store-operated Ca2+ entry (SOCE) activity (PubMed:27185316).
产品来源
洱畔科技实验室
