Anti-C5R1 antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | C5R1 |
| Isotype: | IgG |
| Species immunized: | Rabbit |
| Immunogen: | KLH conjugated synthetic peptide derived from human C5R1 51-150/350 |
| Applications: | Western Blot (1:400-1:2000) |
| Reactivity: | Human, Rat, Dog, Pig, Cow, Rabbit, Sheep, Guinea Pig |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 1*TBS (pH7.4), 1%BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | ANAPHYLATOXIN RECEPTOR |
| C5a anaphylatoxin chemotactic receptor | |
| C5a anaphylatoxin receptor | |
| C5A | |
| C5a ligand | |
| C5a-R | |
| C5aR | |
| C5AR_HUMAN | |
| C5ar1 | |
| C5R1 | |
| CD88 | |
| CD88 antigen | |
| Complement component 5 receptor 1 | |
| Complement component 5 receptor 1 | |
| Complement component 5 receptor 2 |
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靶标信息
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520, PubMed:29300009). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).
产品来源
洱畔科技实验室
