购物车里没有产品

Anti-C18orf1 antibody

产品货号 产品 品牌 单位 存货 价格 促销价 数量  
AB-06-0597
Anti-C18orf1 antibody
洱畔/Erpan Tech 有货

产品特性        

Product type: Primary antibody
Antigen: C18orf1
Immunogen: KLH conjugated synthetic peptide derived from human C18orf1 6-100/306
Species immunized: Rabbit
Isotype: IgG
Applications: Western Blot (1:400-1:2000)
Reactivity: Human, Mouse, Rat, Cow, Sheep
Clonality (clone number): Polyclonal
Form: Liquid
Buffer: 1*TBS (pH7.4), 1%BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration: 1mg/ml
Purity: Protein A affinity purified
Storage: Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles.
Alternative names: C18orf1
Chromosome 18 open reading frame 1
Clone 22
CR001_HUMAN
Hypothetical protein LOC753
展开

靶标信息

Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. Through interaction with SMAD2 and SMAD3, LDLRAD4 may compete with ZFYVE9 and SMAD4 and prevent propagation of the intracellular signal.

产品来源

洱畔科技实验室

文件下载

Material-Safety-Data-Sheet.pdf (下载60986 )