Anti-BACE1 antibody
产品特性
| Product Cat#: | AB-06-0445 |
| Product type: | Primary antibody |
| Antigen: | BACE1 |
| Immunogen: | Peptide C-terminal synthetic BACE peptide of human origin |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:1000); Immunofluorescence (1:100-500); Immunoprecipitation (1-2 μg per 100-500 μg of total protein ); Immunohistochemistry (1:100-1:500) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal, 7H4 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | APP beta secretase antibody |
| Asp 2 antibody | |
| ASP2 antibody | |
| Aspartyl protease 2 antibody | |
| BACE 1 antibody | |
| BACE antibody | |
| BACE1 antibody | |
| BACE1_HUMAN antibody | |
| Beta secretase 1 antibody | |
| Beta secretase antibody | |
| Beta site amyloid beta A4 precursor protein cleaving enzyme antibody | |
| Beta site amyloid precursor protein cleaving enzyme 1 antibody | |
| Beta site amyloid precursor protein cleaving enzyme antibody | |
| Beta site APP cleaving enzyme 1 antibody | |
| Beta site APP cleaving enzyme antibody | |
| Beta-secretase 1 antibody | |
| Beta-site amyloid precursor protein cleaving enzyme 1 antibody | |
| Beta-site APP cleaving enzyme 1 antibody | |
| FLJ90568 antibody | |
| HSPC104 antibody | |
| Memapsin 2 antibody | |
| Memapsin-2 antibody | |
| Memapsin2 antibody | |
| Membrane associated aspartic protease 2 antibody | |
| Membrane-associated aspartic protease 2 antibody | |
| Transmembrane aspartic proteinase Asp2 antibody |
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靶标信息
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. Cleaves APP with much more catalytic efficiency than for the wild-type.
产品来源
洱畔科技实验室
