Anti-ATF6 antibody
产品特性
| Product Cat#: | AB-06-0393 |
| Product type: | Primary antibody |
| Antigen: | ATF6 |
| Immunogen: | Recombinant protein within full length sequence of human ATF6. |
| Species immunized: | Mouse |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:1000); Immunohistochemistry (1:40-1:100); Flow Cytometry (1:40-1:100) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal, 8D3 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 0.5% BSA, 50% glycerol, 0.05% NaN3. |
| Concentration: | 2 mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Activating transcription factor 6 alpha antibody |
| Activating transcription factor 6 antibody | |
| ATF 6 antibody | |
| ATF6 alpha antibody | |
| ATF6 antibody | |
| ATF6-alpha antibody | |
| ATF6A antibody | |
| ATF6A_HUMAN antibody | |
| cAMP dependent transcription factor ATF 6 alpha antibody | |
| cAMP-dependent transcription factor ATF-6 alpha antibody | |
| Cyclic AMP dependent transcription factor ATF 6 alpha antibody | |
| DKFZp686P2194 antibody | |
| ESTM49 antibody | |
| FLJ21663 antibody | |
| Processed cyclic AMP dependent transcription factor ATF 6 alpha antibody | |
| Processed cyclic AMP-dependent transcription factor ATF-6 alpha antibody |
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靶标信息
Transmembrane glycoprotein of the endoplasmic reticulum that functions as a transcription activator and initiates the unfolded protein response (UPR) during endoplasmic reticulum stress. Cleaved upon ER stress, the N-terminal processed cyclic AMP-dependent transcription factor ATF-6 alpha translocates to the nucleus where it activates transcription of genes involved in the UPR. Binds DNA on the 5′-CCAC[GA]-3’half of the ER stress response element (ERSE) (5′-CCAAT-N9-CCAC[GA]-3′) and of ERSE II (5′-ATTGG-N-CCACG-3′). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor. May play a role in foveal development and cone function in the retina.
产品来源
洱畔科技实验室
