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Anti-APC antibody

产品货号 产品 品牌 单位 存货 价格 促销价 数量  
AB-06-0322
Anti-APC antibody
洱畔/Erpan Tech 有货

产品特性        

Product Cat#: AB-06-0322
Product type: Primary antibody
Antigen: APC
Immunogen: Peptide
Species immunized: Rabbit
Isotype: IgG
Applications: Western Blot (1:500); Immunocytochemistry (1:100-1:200); Immunohistochemistry (1:100-1:200); Flow Cytometry (1:100-1:200)
Reactivity: Mouse, Rat and Human
Clonality (clone number): Polyclonal
Form: Liquid
Buffer: Tris-HCl buffer (pH7.4), 1% BSA, 40% Glycerol, 0.05% NaN3.
Concentration: 1 mg/ml
Purity: Protein A/G affinity purified
Storage: Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles.
Alternative names: Adenomatous Polyposis Coli antibody
Adenomatous polyposis coli protein antibody
Apc antibody
APC_HUMAN antibody
CC1 antibody
Deleted in polyposis 2.5 antibody
DP2 antibody
DP2.5 antibody
DP3 antibody
FAP antibody
FPC antibody
GS antibody
Protein APC antibody
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靶标信息

Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization.

产品来源

洱畔科技实验室

文件下载

MSDS-AB-06-0322.pdf (下载234 )