Anti-Annexin A7 antibody
产品特性
| Product Cat#: | AB-06-0306 |
| Product type: | Primary antibody |
| Antigen: | Annexin A7 |
| Immunogen: | KLH conjugated synthetic peptide derived from human Annexin A7 251-350/488 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000) |
| Reactivity: | Human, Mouse, Rat, Dog, Pig, Cow, Rabbit |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Annexin VII |
| AnnexinVII | |
| Annexin A7 | |
| ANX7 | |
| ANXA7 | |
| SNX | |
| Synexin | |
| Annexin-7 |
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靶标信息
Retains NFE2L2/NRF2 in the cytosol. Functions as substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1. Targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. May also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
产品来源
洱畔科技实验室
