Anti-Angiopoietin-2 antibody
产品特性
| Product Cat#: | AB-06-0292 |
| Product type: | Primary antibody |
| Antigen: | Angiopoietin-2 |
| Immunogen: | Amino acids 171-240 mapping within an internal region of the mature chain of Ang-2 of human origin.. |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry (1:40-1:200); Immunofluorescence (1:100-500); Immunoprecipitation (1-2 μg per 100-500 μg of total protein) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal, 4A2 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | AGPT 2 antibody |
| Agpt2 antibody | |
| ANG 2 antibody | |
| ANG-2 antibody | |
| ANG2 antibody | |
| Angiopoietin 2a antibody | |
| Angiopoietin 2B antibody | |
| Angiopoietin-2 antibody | |
| Angiopoietin2 antibody | |
| ANGP2_HUMAN antibody | |
| ANGPT 2 antibody | |
| Angpt2 antibody | |
| Tie2 ligand antibody |
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靶标信息
Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
产品来源
洱畔科技实验室
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