Anti-AMPK beta1 antibody
产品特性
| Product Cat#: | AB-06-0282 |
| Product type: | Primary antibody |
| Antigen: | AMPK beta1 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Flow Cytometry (1:40-1:100) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal, SD082-06 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 1300015D22Rik antibody |
| 5"-AMP-activated protein kinase subunit beta-1 antibody | |
| 5'-AMP-activated protein kinase beta-1 subunit antibody | |
| AAKB1_HUMAN antibody | |
| AMP-activated protein kinase beta subunit antibody | |
| AMP-ACTIVATED PROTEIN KINASE, NONCATALYTIC, BETA-1 antibody | |
| AMP-activated, noncatalytic, beta-1 antibody | |
| AMPK antibody | |
| AMPK beta 1 chain antibody | |
| AMPK subunit beta-1 antibody | |
| AMPK-BETA-1 antibody | |
| AMPKb antibody | |
| AU021155 antibody | |
| E430008F22 antibody | |
| HAMPKb antibody | |
| MGC17785 antibody | |
| PRKAB1 antibody | |
| Protein kinase AMP activated non catalytic subunit beta 1 antibody | |
| Protein kinase, AMP-activated, beta 1 non-catalytic subunit antibody | |
| Protein kinase, AMP-activated, noncatalytic, beta-1 antibody |
靶标信息
Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
产品来源
洱畔科技实验室
