重组Anti-E Cadherin抗体[EP700Y] – Intercellular Junction Marker (ab40772)
产品特性
| Product Cat#: | ab40772 |
| Product type: | Primary antibody |
| Antigen: | E-cadherin |
| Immunogen: | Synthetic peptide within Human E Cadherin aa 600-700. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Flow Cyt (Intra), ICC/IF, mIHC, IHC-P, WB |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal, EP700Y |
| Form: | Liquid |
| Buffer: | pH: 7.20 |
| Preservative: 0.01% Sodium azide | |
| Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.5% BSA | |
| Concentration: | 0.294 mg/ml |
| Purity: | Protein A purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | cadherin 1, E-cadherin (epithelial); cadherin 1, type 1; cadherin 1, type 1, E-cadherin (epithelial); cadherin e; Cadherin-1; cadherin-E; calcium-dependent adhesion protein, epithelial; CAM 120/80; CD324; cell-CAM 120/80; E-Cadherin; E-cadherin 1; Ecadherin; Epithelial cadherin; Uvomorulin; Arc-1; CD324; CDH1; CDHE; ECAD; LCAM; UVO |
靶标信息
Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333).
They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed:11976333).
Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.
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