Anti-C14orf93 antibody
产品特性
| Product type: | Primary antibody |
| Antigen: | C14orf93 |
| Immunogen: | KLH conjugated synthetic peptide derived from human C14ORF140/FAM164C 871-456/456 |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:500-1:1000); Immunohistochemistry (1:100-1:200); Immunocytochemistry (1:100-1:200); Flow Cytometry (1:40-1:200) |
| Reactivity: | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep |
| Clonality (clone number): | Monoclonal, 2-F6 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 0.5% BSA, 0.05% NaN3 and 50% Glycerol. |
| Concentration: | 2mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | C14orf93 antibody |
| CN093_HUMAN antibody | |
| Uncharacterized protein C14orf93 antibody | |
| Uncharacterized protein C14orf93 homolog antibody |
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靶标信息
C14orf93 (also named as Regulator of Thyroid Function and Cancer, RTFC) as a novel susceptibility gene for familial nonmedullary thyroid cancer.The oncogenic functions of R115Q, V205M, and G209D RTFC mutants are demonstrated by cell surviving assay, migration assay, and colony forming assays. Moreover, RTFC has been identified as a potential antigen associated with the pathogenesis of peripheral T-cell lymphomas, not otherwise specified (PTCL, NOS). Two in vitro biochemical screens suggested that RTFC might have RNA and phosphopeptide (pSer/pThr-X-X-X-pSer/pThr) binding activities. Yet, the role of RTFC in normal development, as well as the molecular function of RTFC, remain unexplored.
产品来源
洱畔科技实验室