Anti-Beclin 1 antibody
产品特性
| Product Cat#: | AB-06-0493 |
| Product type: | Primary antibody |
| Antigen: | Beclin 1 |
| Immunogen: | Synthetic peptide (KLH-coupled) within human Beclin 1 aa 380-450 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Immunohistochemistry (1:200); Immunocytochemistry (1:50-1:100) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A/G affinity purified/Antigen affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | APG6 antibody |
| ATG 6 antibody | |
| ATG6 antibody | |
| ATG6 autophagy related 6 homolog antibody | |
| Bcl-2-interacting protein beclin antibody | |
| Beclin 1 (coiled coil moesin like BCL2 interacting protein) antibody | |
| Beclin 1 autophagy related antibody | |
| Beclin-1 antibody | |
| Beclin1 antibody | |
| BECN 1 antibody | |
| Becn1 antibody | |
| BECN1_HUMAN antibody | |
| Coiled coil myosin like BCL2 interacting protein antibody | |
| Coiled-coil myosin-like BCL2-interacting protein antibody | |
| GT197 antibody | |
| Protein GT197 antibody | |
| VPS 30 antibody | |
| VPS30 antibody |
靶标信息
Plays a central role in autophagy (PubMed:23184933, PubMed:28445460). Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123, PubMed:20208530, PubMed:26783301). Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms. Involved in endocytosis (PubMed:25275521). Protects against infection by a neurovirulent strain of Sindbis virus (PubMed:9765397). May play a role in antiviral host defense.
产品来源
洱畔科技实验室
