Mouse Bone Morphogenetic Protein 10 ELISA kit
产品特性
| Product Cat#: | EK-07-0980 | |
| Product name: | Mouse Bone Morphogenetic Protein 10 ELISA kit | |
| Species Reactivity: | Mouse | |
| Target Name: | BMP10 | |
| Product Size: | 48/96 Tests | |
| Sensitivity: | 0.05 ng/ml | |
| Assay range: | 0.5-10 ng/ml | |
| Platform: | Colorimetric Microplate ReaderAssay Time: | 90 minutes |
| Conjugate: | HRP | |
| ELISA Type: | Sandwich ELISA | |
| Detection Method: | Colorimetric | |
| Storage temperature: | Store at 2-8°C | |
| Stability: | Stable within the expiration date under suggested storage conditions | |
| Shipping condition: | Wet ice | |
| Kit Contents: | Microtiter plate (1x), Enzyme conjugate (1 vial), Standard samples (6 vials), | |
| Substrates (A & B, 2 vials), Stop solution (1 vial), Wash Solution (100x, 1 vial), | ||
| Balance solution (1 vial), Instruction (1 copy) | ||
| Other Names of Target: | Bone morphogenetic protein 10; Bone morphogenetic protein 10 preproprotein |
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靶标信息
Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines (By similarity).
产品来源
洱畔科技实验室
