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Anti-NF-κB p65 antibody

SKU Product Brand Unit Availability Price 促销价 Quantity  
AB-06-3129
Anti-NF-κB p65 antibody
洱畔/Erpan Tech In stock

Specifications        

Product Cat#: AB-06-3129
Product type: Primary antibody
Antigen: NF-κB p65
Immunogen: This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to N-terminal NF-κB p65.
Species immunized: Rabbit
Isotype: IgG
Applications: Western Blot (1:500-1:2000); Immunohistochemistry (1:100-1:200); Flow Cytometry (1:50-1:100)
Reactivity: Mouse, Rat and Human
Clonality (clone number): Polyclonal
Form: Liquid
Buffer: 1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration: 1 mg/ml
Purity: Peptide affinity purified
Storage: Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles.
Alternative names: Avian reticuloendotheliosis viral (v rel) oncogene homolog A antibody
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NFKB3 antibody
Nuclear Factor NF Kappa B p65 Subunit antibody
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OTTHUMP00000233473 antibody
OTTHUMP00000233474 antibody
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p65 antibody
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靶标信息

NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. In unstimulated cells, NF-κB is sequestered in the cytoplasm by IκB inhibitory proteins. NF-κB-activating agents can induce the phosphorylation of IκB proteins, targeting them for rapid degradation through the ubiquitin-proteasome pathway and releasing NF-κB to enter the nucleus where it regulates gene expression.

产品来源

洱畔科技实验室

文件下载

MSDSAB-06-3129.pdf (57 downloads )