Anti-Apolipoprotein O antibody
产品特性
| Product Cat#: | AB-06-0350 |
| Product type: | Primary antibody |
| Antigen: | Apolipoprotein E |
| Immunogen: | KLH conjugated synthetic peptide derived from human ApoO/Apolipoprotein O 101-198/198 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-2000) |
| Reactivity: | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep |
| Clonality (clone number): | Monoclonal, SC0536 |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | ApoO |
| 0610008C08Rik | |
| 1110019O03Rik | |
| Apolipoprotein O | |
| APOO | |
| APOO_HUMAN | |
| FAM121B | |
| Family with sequence similarity 121B | |
| MGC130105 | |
| MGC130106 | |
| MGC4825 | |
| My025 | |
| MYO25 | |
| OTTHUMP00000023073 | |
| Protein FAM121B |
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靶标信息
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a crucial role in crista junction formation and mitochondrial function (PubMed:25764979). Can promote cardiac lipotoxicity by enhancing mitochondrial respiration and fatty acid metabolism in cardiac myoblasts (PubMed:24743151). Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP)-dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL (PubMed:16956892).
产品来源
洱畔科技实验室
