Anti-SUMO-1 antibody
产品特性
| Product Cat#: | AB-06-4232 |
| Product type: | Primary antibody |
| Antigen: | SUMO-1 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Co-Immunoprecipitation; Immunoprecipitation; Immunofluorescence; Western Blot (1:100-1:200); Immunohistochemistry (1:100-1:200); Immunocytochemistry (1:100-1:200); Flow Cytometry (1:40-1:100) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal (SJ20-03) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | DAP1 antibody |
| GAP modifying protein 1 antibody | |
| GAP-modifying protein 1 antibody | |
| GMP 1 antibody | |
| GMP1 antibody | |
| OFC10 antibody | |
| PIC 1 antibody | |
| PIC1 antibody | |
| SENP2 antibody | |
| Sentrin 1 antibody | |
| Sentrin antibody | |
| Small ubiquitin related modifier 1 antibody | |
| Small ubiquitin-like modifier 1 antibody | |
| Small ubiquitin-related modifier 1 antibody | |
| SMT3 antibody | |
| SMT3 homolog 3 antibody | |
| SMT3 suppressor of mif two 3 homolog 1 antibody | |
| SMT3, yeast, homolog 3 antibody | |
| Smt3C antibody | |
| SMT3H3 antibody | |
| SUMO-1 antibody | |
| SUMO1 antibody | |
| SUMO1_HUMAN antibody | |
| Ubiquitin homology domain protein PIC1 antibody | |
| Ubiquitin Like 1 antibody | |
| Ubiquitin like protein SMT3C antibody | |
| Ubiquitin like protein UBL1 antibody | |
| Ubiquitin-homology domain protein PIC1 antibody | |
| Ubiquitin-like protein SMT3C antibody | |
| Ubiquitin-like protein UBL1 antibody | |
| UBL 1 antibody | |
| UBL1 antibody |
靶标信息
Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Covalently attached to the voltage-gated potassium channel KCNB1; this modulates the gating characteristics of KCNB1 (PubMed:19223394). Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. May also regulate a network of genes involved in palate development. Covalently attached to ZFHX3 (PubMed:24651376).
产品来源
洱畔科技实验室