Anti-XRN2 antibody
产品特性
| Product cat: | AB-06-4673 |
| Product type: | Primary antibody |
| Antigen: | XRN2 |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:900-1:2400); Immunohistochemistry (1:90-1:260) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 5' 3' exoribonuclease 2 antibody |
| DHM1 like protein antibody | |
| DHP protein antibody | |
| XRN 2 antibody |
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靶标信息
Possesses 5′->3′ exoribonuclease activity (By similarity). May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5′ fragment which is subsequently processed to form the mature mRNA and a 3′ fragment which remains attached to the elongating polymerase. The processive degradation of this 3′ fragment by this protein may promote termination of transcription. Binds to RNA polymerase II (RNAp II) transcription termination R-loops formed by G-rich pause sites (PubMed:21700224).
产品来源
洱畔科技实验室
