Anti-NFIB/NF1B2 antibody
产品特性
| Product Cat#: | AB-06-3117 | |||||||||||||
| Product type: | Primary antibody | |||||||||||||
| Antigen: | NFIB/NF1B2 | |||||||||||||
| Immunogen: | Recombinant full length protein corresponding to human NFIB/NF1B2. | |||||||||||||
| Species immunized: | Mouse | |||||||||||||
| Isotype: | IgG1 | |||||||||||||
| Applications: | Western Blot (1:200-1:2000); Immunohistochemistry(1:100-1:200); Flow Cytometry (1:10-1:100) | |||||||||||||
| Reactivity: | Mouse, Rat and Human | |||||||||||||
| Clonality (clone number): | Monoclonal(1H4) | |||||||||||||
| Form: | Liquid | |||||||||||||
| Buffer: | 1*TBS (pH7.4), 0.5% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide. | |||||||||||||
| Concentration: | 1 mg/ml | |||||||||||||
| Purity: | Protein A affinity purified | |||||||||||||
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. | |||||||||||||
| Alternative names: | CCAAT Box Binding Transcription Factor antibody | CCAAT-box-binding transcription factor antibody | CTF antibody | HMGIC/NFIB antibody | NF-I/B antibody | NF1-B antibody | NF1B antibody | NF1B2 antibody | NFI-B antibody | NFI-RED antibody | Nfib antibody | NFIB_HUMAN antibody | NFIB2 antibody | NFIB3 antibody |
靶标信息
NF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, and activates transcription through a putatively novel, proline-rich, carboxy terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, α-globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.
产品来源
洱畔科技实验室