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Anti-Phospho-Rac1+Cdc42 (S71) antibody

产品货号 产品 品牌 单位 存货 价格 促销价 数量  
AB-06-3540
Anti-Phospho-Rac1+Cdc42 (S71) antibody
洱畔/Erpan Tech 有货

产品特性        

Product Cat#: AB-06-3540
Product type: Primary antibody
Antigen: Phospho-Rac1+Cdc42(Ser71)
Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Ser71 of human CDC42.
Species immunized: Rabbit
Isotype: IgG
Applications: Western Blot (1:400-1:1000); Immunohistochemistry (1:40-1:200); Immunocytochemistry (1:40-1:200); Immunofluorescence
Reactivity: Human
Clonality (clone number): Monoclonal (JJ086-9)
Form: Liquid
Buffer: Tris-HCl buffer (pH7.4), 1% BSA; 40% glycerol, 0.05% NaN3.
Concentration: 1 mg/ml
Purity: Protein A affinity purified
Storage: Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles.
Alternative names: CDC42Hs antibody Cell division cycle 42 antibody G25K antibody MIG5 antibody Migration inducing gene 5 antibody P21 Rac1 antibody Ras like protein TC25 antibody Small GTP binding protein Cdc42 antibody TC25 antibody
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靶标信息

Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase . Regulates cell migration . In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections . Required for DOCK10-mediated spine formation in Purkinje cells and hippocampal neurons. Facilitates filopodia formation upon DOCK11-activation (By similarity). Upon activation by CaMKII, modulates dendritic spine structural plasticity by relaying CaMKII transient activation to synapse-specific, long-term signaling (By similarity). Also plays a role in phagocytosis through organization of the F-actin cytoskeleton associated with forming phagocytic cups.

产品来源

洱畔科技实验室

文件下载

MSDS-AB-06-3540.pdf (下载75 )