Anti-E2F1 antibody
产品特性
| Product Cat#: | AB-06-1479 |
| Product type: | Primary antibody |
| Antigen: | E2F1 |
| Immunogen: | Peptide |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:1000); Immunocytochemistry (1:80-1:200); Flow Cytometry (1:8-1:10); Immunoprecipitation (1:8-1:10) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclona ( 9H2) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1mg/ml |
| Purity: | Tissue culture supernatant |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | DmelCG6376 Antibody |
| Dmel_CG6376 Antibody | |
| drosE2F1 Antibody | |
| E(Sev-CycE)3A Antibody | |
| E(var)3-93E Antibody | |
| E2-promoter Binding Facto Antibody | |
| E2F 1 Antibody | |
| E2F Transcription Factor 1 Antibody | |
| E2F-1 Antibody | |
| E2f-PA Antibody | |
| E2f-PB Antibody | |
| E2f-PC Antibody | |
| E2F1 Antibody | |
| E2f1 E2F Transcription Factor 1 Antibody | |
| E2F1_HUMAN Antibody | |
| Evar(3)164 Antibody | |
| KIAA4009 Antibody | |
| l(3)07172 Antibody | |
| l(3)j3B1 Antibody | |
| l(3)j3C2 Antibody | |
| l(3)rM729 Antibody | |
| mKIAA4009 Antibody | |
| OTTHUMP00000030661 Antibody | |
| PBR3 Antibody | |
| PRB Binding Protein E2F 1 Antibody | |
| PRB-binding Protein E2F-1 Antibody | |
| RBAP 1Antibody | |
| RBAP-1 Antibody | |
| RBAP1 Antibody | |
| RBBP-3 Antibody | |
| RBBP3 Antibody | |
| RBP 3 Antibody | |
| RBP3 Antibody | |
| Retinoblastoma-associated Protein 1 Antibody | |
| Retinoblastoma-binding Protein 3 Antibody | |
| Transcription Factor E2F1 Antibody |
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靶标信息
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5′-TTTC[CG]CGC-3′ found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters (PubMed:20176812). Positively regulates transcription of RRP1B (PubMed:20040599).
产品来源
洱畔科技实验室