Anti-CCDC111 antibody
产品特性
| Product Cat#: | AB-06-0801 |
| Product type: | Primary antibody |
| Antigen: | CCDC111 |
| Immunogen: | This antibody is produced by immunizing mice with recombinant protein of human CCDC111. |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Immunohistochemistry (1:210); Immunocytochemistry (1:90-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (10-B3) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 2 mg/ml |
| Purity: | Protein G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CC111_HUMAN antibody |
| CCDC111 antibody | |
| Coiled coil domain containing 111 antibody | |
| Coiled-coil domain-containing protein 111 antibody | |
| DNA-directed primase/polymerase protein antibody | |
| MYP22 antibody | |
| Primase and polymerase (DNA directed) antibody | |
| PRIMPOL antibody |
展开
靶标信息
DNA primase and DNA polymerase able to initiate de novo DNA synthesis using dNTPs. Shows a high capacity to tolerate DNA damage lesions such as 8oxoG and abasic sites in DNA. Involved in translesion synthesis via its primase activity by mediating uninterrupted fork progression after programmed or damage-induced fork arrest and by reinitiating DNA synthesis after dNTP depletion. Required for mitochondrial DNA (mtDNA) synthesis, suggesting it may be involved in DNA tolerance during the replication of mitochondrial DNA. Has non-overlapping function with POLH.
产品来源
洱畔科技实验室