Anti-Choline Acetyltransferase antibody
产品特性
| Product type: | Primary antibody |
| Antigen: | Choline Acetyltransferase |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:1000); Immunohistochemistry (1:40-1:200); Flow Cytometry (1:40-1:100); Immunocytochemistry (1:40-1:200); Immunoprecipitation (1:15-1:50); Immunofluorescence |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (JA67-11) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Acetyl CoA choline O acetyltransferase antibody |
| Acetyl CoA:choline O acetyltransferase antibody | |
| ChAT antibody | |
| CHOACTase antibody | |
| Choline acetylase antibody | |
| Choline acetyltransferase antibody | |
| Choline O acetyltransferase antibody | |
| Choline O-acetyltransferase antibody | |
| CLAT_HUMAN antibody | |
| CMS1A antibody | |
| CMS1A2 antibody | |
| EC 2.3.1.6 antibody | |
| OTTHUMP00000019583 antibody | |
| OTTHUMP00000019584 antibody |
展开
靶标信息
Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5′-CCTTTGATC-3′ in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1. Expression of dominant-negative mutants results in cell-cycle arrest in G1. Necessary for the maintenance of the epithelial stem-cell compartment of the small intestine.
产品来源
洱畔科技实验室