Anti-PICK1 antibody
产品特性
| Product Cat#: | AB-06-3581 |
| Product type: | Primary antibody |
| Antigen: | PICK1 |
| Immunogen: | Recombinant protein within N-terminal human PICK1 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:2000-1:5000); Immunoprecipitation (1:10-1:50); Flow Cytometry (1:100-1:200) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (JG30-80) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | dJ1039K5 antibody |
| MGC15204 antibody | |
| OTTHUMP00000028509 antibody | |
| PICK 1 antibody | |
| Pick1 antibody | |
| PICK1_HUMAN antibody | |
| PRKCA binding protein antibody | |
| PRKCA-binding protein antibody | |
| PRKCABP antibody | |
| Protein Interacting with C Kinase 1 antibody | |
| Protein Interacting with PRKCA antibody | |
| Protein Interacting with PRKCA 1 antibody | |
| Protein Kinase C Alpha Binding Protein antibody | |
| Protein Kinase C-Alpha-Binding Protein antibody | |
| Protein that Interacts with C Kinase 1 antibody |
靶标信息
Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
产品来源
洱畔科技实验室