Anti-Phospho-Tau (T231) antibody
产品特性
| Product Cat#: | AB-06-3565 | |||||||||||||||||||||||||||||
| Product type: | Primary antibody | |||||||||||||||||||||||||||||
| Antigen: | Phospho-Tau (T231) | |||||||||||||||||||||||||||||
| Immunogen: | Synthetic phospho-peptide corresponding to residues surrounding Thr231 of human Tau | |||||||||||||||||||||||||||||
| Species immunized: | Rabbit | |||||||||||||||||||||||||||||
| Isotype: | IgG | |||||||||||||||||||||||||||||
| Applications: | Western Blot (1:1000); Immunohistochemistry (1:50-1:200); Immunoprecipitation | |||||||||||||||||||||||||||||
| Reactivity: | Human, Mouse, Rat | |||||||||||||||||||||||||||||
| Clonality (clone number): | Monoclonal (SC58-08) | |||||||||||||||||||||||||||||
| Form: | Liquid | |||||||||||||||||||||||||||||
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% Glycerol, 0.05% NaN3. | |||||||||||||||||||||||||||||
| Concentration: | 1 mg/ml | |||||||||||||||||||||||||||||
| Purity: | Protein A affinity purified | |||||||||||||||||||||||||||||
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. | |||||||||||||||||||||||||||||
| Alternative names: | AI413597 antibody | AW045860 antibody | DDPAC antibody | FLJ31424 antibody | FTDP 17 antibody | G protein beta1/gamma2 subunit interacting factor 1 antibody | MAPT antibody | MAPTL antibody | MGC134287 antibody | MGC138549 antibody | MGC156663 antibody | Microtubule associated protein tau antibody | Microtubule associated protein tau isoform 4 antibody | Microtubule-associated protein tau antibody | MSTD antibody | Mtapt antibody | MTBT1 antibody | MTBT2 antibody | Neurofibrillary tangle protein antibody | Paired helical filament tau antibody | Paired helical filament-tau antibody | PHF tau antibody | PHF-tau antibody | PPND antibody | PPP1R103 antibody | Protein phosphatase 1, regulatory subunit 103 antibody | pTau antibody | RNPTAU antibody | TAU antibody | TAU_HUMAN antibodyTauopathy and respiratory failure, included antibody |
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靶标信息
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
产品来源
洱畔科技实验室