Anti-CD151 antibody
产品特性
| Product Cat#: | AB-06-0858 |
| Product type: | Primary antibody |
| Antigen: | CD151 |
| Immunogen: | Peptide |
| Species immunized: | Mouse |
| Isotype: | IgG |
| Applications: | Western Blot ( 1:800-1:2000 ); Immunoprecipitation ( 1-2 μg per 100-500 μg of total protein ( 1 ml of cell lysate ) ); Immunofluorescence ( 1:80-1:500 ); Immunohistochemistry-Paraffin ( 1:500-800 ) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal ( 3G1 ) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer ( pH7.4 ), 1 % BSA, 40 % glycerol, 0.05 % NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CD151 Antibody |
| CD151 Antigen Antibody | |
| CD151 Molecule (Raph Blood Group) Antibody | |
| CD151 Molecule Antibody | |
| CD151_HUMAN Antibody | |
| GP27 Antibody | |
| Hemidesmosomal Tetraspanin CD151 Antibody | |
| Membrane Glycoprotein SFA-1 Antibody | |
| MER2 Antibody | |
| PETA-3 Antibody | |
| PETA3 Antibody | |
| Platelet Endothelial Tetraspan Antigen 3 Antibody | |
| platelet Surface Glycoprotein gp27 Antibody | |
| Platelet-endothelial Cell Tetraspan Antigen 3 Antibody | |
| Platelet-endothelial Tetraspan Antigen 3 Antibody | |
| RAPH Antibody | |
| Red blood Cell Antigen MER2 Antibody | |
| SFA 1 Antibody | |
| SFA1 Antibody | |
| Tetraspanin-24Antibody | |
| Tspan-24 Antibody | |
| TSPAN24 Antibody |
靶标信息
CD151 is involved in a wide variety of cell biological processes, includingcell adhesion and the transport of integrins via vesicles. The human CD151gene maps to chromosome 11p15.5 and encodes a 253 amino acid protein,which belongs to the tetraspan (4TM) superfamily. CD151 can associate with several Integrin chains including β1, β3, β4, α2, α3, α5 and α6 integrins. CD151 may provide a framework for the spatial organization of both type I and type II hemidesmosomes, which are specialized junctional complexes that function as cell-attachment sites for binding to basement membranes. CD151 RNA transcript (1.6 kb) can be detected in MO7e cells, bone marrow stromal cells, C11 endothelial cells, HUVEC and several myeloid leukemia cell lines, however, no transcript is detected in brain and the lymphoblastoid cell lines MOLT-4 and BALM-1. Leu149 -Glu213 of CD151 is the interface through which Integrins α3/β1 can bind. CD151 can enhance cell motility, invasion and metastasis of cancer cells in a focal adhesion kinase dependent manner.
产品来源
洱畔科技实验室
