Anti-Cytochrome C antibody
产品特性
| Product Cat#: | AB-06-1261 | ||||||
| Product type: | Primary antibody | ||||||
| Antigen: | Cytochrome C | ||||||
| Immunogen: | Synthetic peptide (KLH-coupled) | ||||||
| Species immunized: | Rabbit | ||||||
| Isotype: | IgG | ||||||
| Applications: | Western Blot (1:1000-1:5000); Immunohistochemistry (1:50-1:200); Immunocytochemistry (1:50-1:200); Flow Cytometry (1:50-1:100) | ||||||
| Reactivity: | Human, Mouse, Rat | ||||||
| Clonality (clone number): | Polyclonal | ||||||
| Form: | Liquid | ||||||
| Buffer: | Tris-HCl buffer (pH7.4), 0.5% BSA, 50% glycerol, 0.05% NaN3. | ||||||
| Concentration: | 1 mg/ml | ||||||
| Purity: | Peptide affinity purified | ||||||
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. | ||||||
| Alternative names: | CYC antibody | CYC_HUMAN antibody | CYCS antibody | Cytochrome c antibody | Cytochrome c somatic antibody | HCS antibody | THC4 antibody |
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靶标信息
Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
产品来源
洱畔科技实验室
