Anti-PP2A (alpha+beta) antibody
产品特性
| Product type: | Primary antibody |
| Antigen: | PP2A (alpha+beta) |
| Immunogen: | Peptide |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:2000); Immunohistochemistry-Paraffin (1:60-1:200); Immunocytochemistry (1:60-1:200); Flow Cytometry (1:40-1:100) |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Peptide affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | PP2A A antibody |
| PP2A alpha antibody | |
| PP2A B antibody | |
| PP2A beta antibody | |
| PP2A-alpha antibody | |
| PP2AA_HUMAN antibody | |
| PP2Ac antibody | |
| PP2CB antibody | |
| PPP2CA antibody | |
| PPP2CB antibody | |
| Protein phosphatase 2 catalytic subunit alpha isoform antibody | |
| Protein phosphatase 2 catalytic subunit beta isoform antibody | |
| Replication protein C antibody | |
| RP C antibody | |
| RP-C antibody | |
| Serine/threonine protein phosphatase 2A catalytic subunit alpha isoform antibody | |
| Serine/threonine protein phosphatase 2A catalytic subunit beta isoform |
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靶标信息
PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at ‘Ser-259’.
产品来源
洱畔科技实验室