Anti-CRTC2 antibody
产品特性
| Product Cat#: | AB-06-1173 |
| Product type: | Primary antibody |
| Antigen: | CRTC2 |
| Immunogen: | Purified recombinant fragment of human CRTC2 expressed in E. Coli |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:500-1:1000); Flow Cytometry (1:100-1:200); Immunocytochemistry (1:50-1:200); Immunohistochemistry (1:50-1:200) |
| Reactivity: | Human, Monkey |
| Clonality (clone number): | Monoclonal (D2-B10) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CREB regulated transcription coactivator 2 antibody |
| CREB-regulated transcription coactivator 2 antibody | |
| CRTC2 antibody | |
| CRTC2_HUMAN antibody | |
| RP11-422P24.6 antibody | |
| TORC-2 antibody | |
| Torc2 antibody | |
| Transducer of CREB protein 2 antibody | |
| Transducer of regulated cAMP response element-binding protein antibody | |
| Transducer of regulated cAMP response element-binding protein (CREB) 2 antibody |
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靶标信息
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 ‘Ser-133’ phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
产品来源
洱畔科技实验室