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Anti-HDAC7 antibody

产品货号 产品 品牌 单位 存货 价格 促销价 数量  
AB-06-2112
Anti-HDAC7 antibody
洱畔/Erpan Tech 有货

产品特性        

Product Cat#: AB-06-2112
Product type: Primary antibody
Antigen: HDAC7
Immunogen: recombinant protein
Species immunized: Rabbit
Isotype: IgG
Applications: Western Blot (1:200-1:2000); Flow Cytometry (1:50-1:200)
Reactivity: Mouse, Rat and Human
Clonality (clone number): Monoclonal (SD082-4)
Form: Liquid
Buffer: 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Concentration: 1 mg/ml
Purity: ProA affinity purified
Storage: Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles.
Alternative names: DKFZP586J0917 antibody
FLJ99588 antibody
HD 7a antibody
HD7 antibody
HD7a antibody
HDAC 7 antibody
HDAC 7A antibody
Hdac7 antibody
HDAC7_HUMAN antibody
HDAC7A antibody
Histone deacetylase 7 antibody
Histone deacetylase 7A antibody
OTTHUMP00000202813 antibody
OTTHUMP00000202814 antibody

 

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靶标信息

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By similarity). May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene. Positively regulates the transcriptional repressor activity of FOXP3 (PubMed:17360565). Serves as a corepressor of RARA, causing its deacetylation and inhibition of RARE DNA element binding (PubMed:28167758). In association with RARA, plays a role in the repression of microRNA-10a and thereby in the inflammatory response (PubMed:28167758).

产品来源

洱畔科技实验室

文件下载

MSDS-AB-06-2112.pdf (下载161 )